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Post Doctoral Fellowship, Respiratory molecular pharmacology: Asthma therapeutics, Airways Inflammation Research Group

Job ID: 15745

Updated: June 13, 2018

Location: Foothills Campus

Position Description

Area: Respiratory molecular pharmacology: Asthma therapeutics                           
Duration: Two years, with potential for extension        
Start Date: Position available immediately, start date negotiable             
Salary:   ≥$45,000/year plus benefits – negotiable based on qualifications and experience

The Airways Inflammation Research Group in the Cumming School of Medicine at the University of Calgary is accepting applications for a Postdoctoral Scholar to study transcriptional control by glucocorticoids and long-acting ß2-adrenoceptor agonists (LABAs) in the context of asthma.

Job Description:

Successful candidates will be recent PhD graduates with the adaptability to explore and understand the complexities of transcriptional control by anti-inflammatory glucocorticoids and long-acting ß2-adrenoceptor agonists. These drug combinations are central to the clinical management of asthma – our goal is to characterize and elucidate mechanisms by which they interact and thereby promote the development of improved combination therapies. We use cutting-edge molecular approaches to investigate transcriptional control by these drugs in vitro and in vivo.

Work in the Newton lab takes place within a dynamic and collaborative environment, involving clinical and basic researchers in the Airways Inflammation Research Group and external collaborations. The lab has CIHR, NSERC and contract funding from Pharma.

The project will involve:

  • Standard molecular skills (western blotting, RNA extraction, qPCR, mammalian cell culture, ELISA)
  • Performing and analysis of ‘omic’ data (RNA-seq, ChIP-seq)
  • Cloning, over-expression, construction of reporter plasmids, RNA silencing, ChIP-PCR, CRISPR

Qualifications:

The successful candidate will hold a PhD (or MD) and have a record of creativity in developing research strategies/approaches. A foundation in one or more of the following: transcriptional control, gene expression analysis, signaling or genomics will be essential. Appropriate computational skills/experience with analysis of ‘omic’ datasets, including gene ontology and/or statistical analyses using R, would be a considerable benefit. The successful candidate will: be a team player, help develop other lab members, be self-motivated, have strong written and verbal communication skills and show evidence of scientific accomplishment.

Application details:  

Applications by e-mail to: Susan Hopkin at shopkin@ucalgary.ca with the subject line “Respiratory Molecular Pharmacology PDF”.  Please include:

  • Cover message/letter describing previous work, career goals, and potential start date
  • full CV / resume
  • Contact information for three referees. 

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.  The University of Calgary respects, appreciates, and encourages diversity.

Questions may be directed to: Dr. Newton at rnewton@ucalgary.ca

Professor, Department of Cell Biology & Anatomy, Airways Inflammation Research Group, Cumming School of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1.

The application deadline is August 15, 2018 (an exceptional candidate could be accepted prior to this).

Additional Information

To learn more about academic opportunities at the University of Calgary and all we have to offer, view our Academic Careers website. For more information about the Cumming School of Medicine visit Careers in the Cumming School of Medicine.

About the University of Calgary
 
The University of Calgary is Canada’s leading next-generation university – a living, growing and youthful institution that embraces change and opportunity with a can-do attitude. Located in the nation’s most enterprising city, the university is making tremendous progress on its Eyes High journey to be recognized as one of Canada’s top five research universities, grounded in innovative learning and teaching and fully integrated with the community it both serves and leads. The University of Calgary inspires and supports discovery, creativity and innovation across all disciplines. For more information, visit ucalgary.ca.
 
About Calgary, Alberta

Calgary is one of the world's cleanest cities and has been named one of the world's most livable cities for years. Calgary is a city of leaders - in business, community, philanthropy and volunteerism. Calgarians benefit from a growing number of world-class dining and cultural events and enjoy more days of sunshine per year than any other major Canadian city. Calgary is less than an hour's drive from the majestic Rocky Mountains and boasts the most extensive urban pathway and bikeway network in North America. 

 

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